Fioricet Drug Interaction

Fioricet contains Butalbital, Acetaminophen, and caffeine.  A lot of other pain relievers contain Butalbital, Acetaminophen, and caffeine too.

I can only list some common over the counter medicines that contain Acetaminophen:  Actifed, Alka-Seltzer, Plus Liquid Gels, Anacin, Cepacol, Contac, Coricidin, Dayquil, Dimetapp, Dristan, Excedrin, Feverall …

Some prescriptions that contain acetaminophen are: Ultrace, Fioricet, Oxycodone, Endocet, Tylox …

FioricetInteractionwithothers

You also must know what drugs contain Butalbital:  Bupap, Phrenilin, Tencon, Cephadyn; Fioricet, Esgic, Esgic-Plus; Fioricet with Codeine, Floricet with Codeine, Phrenilin with Caffeine and Codeine; Axotal; Fiorinal, Butalbital Compound, Farbital, Idenal; Fiorinal with Codeine, Fiorinal with Codeine III, Ascomp with Codeine, Fiortal with Codeine.

When you take more than one pain killer, you must read very carefully about their components.  Never exceed the max dosage of acetaminophen and butalbital of all the medicines you are taking.   Normally All the packages sent to you have the drug introduction and doctor names and phone number.  Read the drug introduction very carefully and never share the medicines with your sisters, your brothers,  your parents, or any friends. Always do not let the children touch the medicines.

Please donot drink any alcohol (Ethanol) with your Fioricet Because Ethanol together with acetaminophen will cause serious side effects that affect your liver, and Ethanol together with Butalbital will cause side effects of dizziness, drowsiness.

Please don’t take herb while you are taking Fioricet. Even Vitamins will have some interaction with Fioricet.

Be honest to place the current medicines you are taking in the health questionnaire  form. The doctor will check whether you are OK to take Fioricet.  If they think your current drugs or herbs have some interaction with Fioricet, they will phone you to discuss the situation with you. So please always leave us the correct phone number. We will never call you to promote you anything.

Most frequently checked interactions

View interaction reports for Fioricet (acetaminophen / butalbital / caffeine) and the medicines listed below.

  • Adderall (amphetamine / dextroamphetamine)
  • Advil (ibuprofen)
  • Ambien (zolpidem)
  • aspirin
  • Ativan (lorazepam)
  • baclofen
  • caffeine
  • clonazepam
  • codeine
  • Cymbalta (duloxetine)
  • Excedrin (acetaminophen / aspirin / caffeine)
  • Flexeril (cyclobenzaprine)
  • gabapentin
  • hydrocodone
  • ibuprofen
  • Imitrex (sumatriptan)
  • Klonopin (clonazepam)
  • levothyroxine
  • Lexapro (escitalopram)
  • lisinopril
  • Lyrica (pregabalin)
  • meloxicam
  • naproxen
  • Norco (acetaminophen / hydrocodone)
  • omeprazole
  • oxycodone
  • Percocet (acetaminophen / oxycodone)
  • prednisone
  • Suboxone (buprenorphine / naloxone)
  • Topamax (topiramate)
  • tramadol
  • trazodone
  • Tylenol (acetaminophen)
  • Vitamin D3 (cholecalciferol)
  • Xanax (alprazolam)
  • Zofran (ondansetron)

 

What should I avoid while I am taking Fioricet?

Fioricet can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid drinking alcohol. It may increase your risk of liver damage while taking acetaminophen.

Ask a doctor or pharmacist before using any other cold, allergy, pain, or sleep medication. Acetaminophen (sometimes abbreviated as APAP) is contained in many combination medicines. Taking certain products together can cause you to get too much acetaminophen which can lead to a fatal overdose. Check the label to see if a medicine contains acetaminophen or APAP.

While you are taking Fioricet, avoid taking diet pills, caffeine pills, or other stimulants (such as ADHD medications) without your doctor’s advice.

Medicines that interact with Fioricet may either decrease its effect, affect how long it works for, increase side effects, or have less of an effect when taken with Fioricet. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Speak to your doctor about how drug interactions should be managed.

Common medications that may interact with Fioricet include:

  • antidepressants, such as tricyclic antidepressants (eg, amitriptyline), monoamine oxidase inhibitors (eg, isocarboxazid, phenelzine, and tranylcypromine), or SSRIs (eg, fluoxetine, sertraline)
  • anticonvulsants, such as carbamazepine, divalproex, lamotrigine, phenytoin, phenobarbital, or primidone
  • antipsychotics (such as butyrophenones, phenothiazines, or thioxanthenes) and atypical antipsychotics (eg, olanzapine, quetiapine, ziprasidone)
  • any medication that may cause drowsiness, such as amphetamines, benzodiazepines (eg, diazepam, lorazepam), first-generation antihistamines (such as doxylamine or promethazine), metoclopramide, or opioids (such as codeine, fentanyl or morphine)
  • buprenorphine
  • cannabis
  • cyclosporine
  • dextromethorphan
  • duloxetine
  • heart medications such as diltiazem or verapamil
  • HIV medications such as ritonavir
  • migraine medications, such as ergotamine or dihydroergotamine
  • muscle relaxants, such as cyclobenzaprine
  • naltrexone
  • other medications that contain acetaminophen or an opioid either in combination or as the sole ingredient
  • pentazocine
  • prilocaine
  • rifampin
  • sodium oxybate
  • tamsulosin
  • tramadol
  • warfarin.

How to treat Fioricet overdose ?

Normally fioricet contains Acetaminophen 325 mg, butalbital 50 mg, and caffeine 40 mg. New fioricet formulation contains  Acetaminophen 300 mg, butalbital 50 mg, and caffeine 40 mg.

fioricet

First and foremost before looking at the specific Fioricet dosage guidelines, it’s important for people to realize that following these guidelines and also their doctor’s instructions with this medicine are incredibly important. Fioricet contains acetaminophen, which while it is available over-the-counter in medicines like Tylenol, can cause liver toxicity when high amounts are taken.

Fioricet contains a black box warning because of the relationships between acetaminophen and acute liver failure. There have been users of not only Fioricet but other medicines containing acetaminophen that have required a liver transplant or have died as a result of the ingredient.

Usually, acetaminophen becomes problematic or fatal at doses of 4,000 mg or more a day. Some of the people most at risk for liver problems related to Fioricet and acetaminophen include people who have existing liver disease, take more than one medicine with acetaminophen in it at a time, or who drink alcohol while using it.

Also relevant to Fioricet dosage instructions is the butalbital ingredient this medicine contains. This ingredient is a barbiturate, and it may be habit-forming. It’s also a central nervous system depressant, so taking too much can result in respiratory depression and overdose.

With that being said, the recommended Fioricet dosage for most adults is to take one to two tablets every four hours as needed for pain, and no more than six tablets should be taken a day. Also part of the Fioricet dosage instructions is the fact that this drug shouldn’t be used long term because of the potential for dependence and abuse.

If someone doesn’t follow the Fioricet dosage instructions, they’re more likely to become ill or overdose from the toxicity of the acetaminophen and the butalbital, rather than the caffeine. Signs you may have overdosed on Fioricet include confusion or extreme drowsiness.

If you miss a dosage of Fioricet, the medicine’s instructions advise to take it when you remember, unless it’s close to the time for your next dosage. Doubling up on dosages is dangerous and can be deadly.

Dangers of Risky Butalbital Use

Butalbital, a generalized central nervous system depressant, may be habit-forming. Butalbital is a commonly misused and abused drug. In fact, consuming butalbital over a long period may result in tolerance, making it necessary to take increasing amounts to produce the same effect. Tolerance to a fatal dosage does not increase more than twofold. This causes the margin between taking a dosage that results in intoxication and taking a fatal dosage to shrink. Taking large quantities of butalbital can result in dangerous consequences, including death.

Recognize the Warning Signs of Misuse

An overdose on butalbital may result from an accidental or intentional act of taking more than the normal or recommended dosage. Overdoses on butalbital may result in toxicity. Signs of an overdose on butalbital include:

  • Confusion
  • Faulty judgment
  • Slowness of speech
  • Slurred speech
  • Extreme sleepiness
  • Sluggishness or hyporeflexia
  • Lack of coordination
  • Respiratory depression
  • Staggering
  • High blood pressure
  • Bradycardia
  • Hypovolemic shock
  • Hypothermia
  • Limp muscles
  • Apnea
  • Coma

“Butalbital overdose symptoms themselves are very serious.”Butalbital overdose symptoms themselves are very serious. A single overdose can result in permanent brain damage or death, particularly if a large amount of butalbital is ingested and treatment is delayed. You need to seek immediate addiction treatment if you experience any signs of an overdose on butalbital. Show your body an act of kindness and become free from butalbital.

Babies born to mothers who took medications containing butalbital while pregnant may exhibit withdrawal or addiction symptoms or breathing problems. Pregnant or nursing women should not take medications containing butalbital unless their doctor feels the benefits of the drug outweigh the risks. Taking butalbital while pregnant may result in miscarriage.

There is a high likelihood that combining butalbital with another drug or drugs will enhance its effects and those of the other drug(s). Individuals mixing this drug with alcohol or other drugs may experience life-threatening overdose symptoms. A lethal dose of butalbital is lower if alcohol is mixed with it. While taking butalbital, you should not consume alcohol or take other drugs not prescribed by your doctor.

Drugs.com indicates approximately one in 10 people who have overdosed on a barbiturate, such as butalbital, or a mixture of drugs including barbiturates will experience fatal consequences because of heart and lung complications. The death rate of barbiturate overdoses can be higher than 10 percent if treatment is delayed. Numerous famous people have died because of barbiturate overdoses.

Emergency Treatment for Fioricet Overdose

Re-establishing or maintaining sufficient respiratory exchange is crucial in butalbital overdose treatment. This can be accomplished through the use of medically assisted detox or controlled ventilation. Severe respiratory depression resulting from a butalbital overdose can be treated with the opioid antagonist naloxone hydrochloride. Naloxone hydrochloride is preferably administered intravenously and simultaneously with respiratory resuscitation efforts. Butalbital overdose treatment can also include the following as needed:

  • Oxygen
  • Induction of vomiting mechanically (individual is unconscious) or with syrup of ipecac (individual is alert)
  • Intravenously administered fluids
  • Intravenously administered vitamin K
  • Vasopressor agents, such as norepinephrine or phenylephrine hydrochloride
  • Intravenously administered norepinephrine bitatrate with serial blood pressure monitoring
  • Emptying the stomach to remove any unabsorbed butalbital
  • Urine alkalinization
  • Oral-activated charcoal
  • Other supportive measures

If the butalbital overdose results in methemoglobinemia that covers over 30 percent of the body, it should be treated with a slow intravenous administration of methylene blue.

Taking more than the prescribed dosage of the drug or taking it when it is not prescribed to you can cause serious butalbital overdose symptoms that may result in fatal consequences. Addiction to butalbital can have very serious or even fatal consequences. If you are worried that your use of the drug may cause you to experience butalbital overdose symptoms, look into your butalbital detox and withdrawal treatment options.

Fioricet Cautions and Warnings

Fioricet contains a combination of acetaminophen, butalbital, and caffeine. Butalbital is a short to intermediate-acting barbiturate and is habit-forming and potentially abusable.  Consequently, the extended use of this product is not recommended. Acetaminophen is used to relieve mild to moderate pain from headaches, muscle aches, menstrual periods, colds and sore throats, toothaches, backaches, and reactions to … Continue reading “Fioricet Cautions and Warnings”

Fioricet contains a combination of acetaminophen, butalbital, and caffeine. Butalbital is a short to intermediate-acting barbiturate and is habit-forming and potentially abusable.  Consequently, the extended use of this product is not recommended.

Acetaminophen is used to relieve mild to moderate pain from headaches, muscle aches, menstrual periods, colds and sore throats, toothaches, backaches, and reactions to vaccinations (shots), and to reduce fever. Caffeine is a methylxanthine similar to theophylline and theobromine. While caffeine is used for stimulant and mood-elevating effects in drinks such as coffee, it also has been used to treat neonatal apnea and headaches in combination with other analgesics.

Following image is the ingredient of fioricet.

 the ingredient of fioricet

The average daily dose for the barbiturate addict is usually about 1500 mg.  But the lethal dose of a barbiturate is far less if alcohol is also ingested. It is strictly required not taking alcohol while you are taking fioricet. One of the important ingredient is acetaminophen. A lot of drugs contains acetaminophen.

More than 600 medicines contain acetaminophen. These medicines include both prescription medicines and OTC medicines. On prescription labels, acetaminophen is sometimes listed as “APAP,” “acetam,” or other shorted versions of the word.  Please read very carefully when you are taking the medicines that contains APAP because overdose of acetaminophen will hurt your heart, liver,  and kidney seriously.  To know what is in your medicines, read the list of active ingredients on the label each and every time you take a medicine. Following picture is a list of some OTC or prescription drugs that contain acetaminophen.

drugs that contains acetaminophen

When you take drugs for pain relief. Please check whether the drug contains apap. You cannot take more than 4000mg acetaminophen per day.

Liver Damage While taking Acetaminophen

The safety dosage is 3000mg per day.  Acetaminophen has been associated with cases of acute liver failure, at times resulting in liver transplant and death. Most of the cases of liver injury are associated with the use of acetaminophen at doses that exceed 4000 milligrams per day, and often involve more than one acetaminophen-containing product.  According to the FDA, in the United States there were “56,000 emergency room visits, 26,000 hospitalizations, and 458 deaths per year related to acetaminophen-associated overdoses during the 1990s. Within these estimates, unintentional acetaminophen overdose accounted for nearly 25% of the emergency department visits, 10% of the hospitalizations, and 25% of the deaths.” [1]

Pregnancy and nursing mom warning while taking fioricet

Acetaminophen; butalbital; caffeine components may all be excreted to some extent into breast milk.  According to the manufacturer, because many drugs are excreted in human milk and because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug. Caffeine can accumulate in the neonate. Chronic barbiturate use while breast-feeding may cause dependence in the neonate. The chronic use of acetaminophen, butalbital, caffeine during breast-feeding is not recommended.

Serious Skin Reactions
Rarely, acetaminophen may cause serious skin reactions such as acute generalized exanthematous pustulosis (AGEP), Stevens-Johnson Syndrome, and toxic epidermal necrolysis (TEN), which can be fatal. Patients should be informed about the signs of serious skin reactions, and use of the drug should be discontinued at the first appearance of skin rash or any other sign of hypersensitivity.

Other warnings
other serious warning is listed in our first page. Following Patients can not buy Fioricet Online.

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